In the Regenerative Medicine Technologies(RMT) Lab
Research EnvironmentThe RMT Lab is part of the Laboratories for Translational Research of Ente Ospedaliero Cantonale (EOC) located in Bellinzona (Switzerland). EOC has a joint research strategy with Università della Svizzera italiana (USI), and the candidate will be enrolled in the Biomed PhD program at USI.
Strategic research areas of the RMT Lab are: in vitro disease modeling through biofabrication (e.g. age-related diseases, cancer metastases, musculo-skeletal diseases);design of novel technologies for drug screening; personalized medicine applications using human tissue biopsies. To promote the advancement of these research areas, the RMT Lab combines microfluidics and microphysiological systems, 3D (bio)printing and computational simulations.
In the framework of these strategic areas, the RMT Lab is pleased to announce an open position:
Dissecting the role of senescence in the bone environment in the progression of bone metastatic prostate cancer.
The project is funded by the Swiss National Science Foundation in collaboration with the Molecular Oncology Lab at the Institute for Oncological Research.
Planned research activities include investigation of the crosstalk between prostate cancer cells and a 3D model of aged bone tissue through imaging, molecular and functional analyses; genomic analyses on cultured cells to elucidate activated pathways and screening of the effects of senolytic drugs on metastatic progression.
Qualifications of the candidates and how to applyWe are looking for a PhD student to join our interdisciplinary research team.What we would like from you:
• Self-motivation and commitment to experimental goals and deadlines
• Master in Life sciences fields
• Strong organizational skills and ability to work independently as well as in a team
• Critical data analysis and troubleshooting
• Effectively communicate experimental data, maintain records and write protocols
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• Creative thinking
• Experience in cell culture (preferred if 3D culture with hydrogels); imaging (confocal microscopy, preferably with 3D cultures); standard biological techniques (e.g.
Candidates are encouraged to send CV, publication list, cover letter including research interests and career goals (max 1 page), 2 references (reference letters are welcome but not required at this stage)
Contact: rmtlab@eoc.ch (please use the following subject: PhD SNF)
mailto:rmtlab@eoc.ch
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