Job Description
We are seeking a highly motivated and skilled Postdoctoral Fellow in Chemical Data Science to contribute to an innovative research project at ETH Zurich and Synple Chem. The successful candidate will collaborate with Professor Jeffrey Bode and his team, as well as researchers from Synple Chem, to develop an intelligent automated synthesis platform.
Project Background
The overarching goal of this project is to combine the expertise of the Bode group in synthesis and reaction outcome prediction with Synple Chem's synthesis automation capabilities. This collaboration aims to improve and expand Synple Chem's existing synthesis automation platform by increasing throughput and enhancing its self-learning nature.
Key Responsibilities
* Collaborate with synthetic chemists to integrate synthetic predictions and reaction automation.
* Develop and apply innovative active-learning strategies for reaction optimization and automation-friendly protocols.
* Create systems for capturing, managing, querying, and exploring experimental data generated during reaction optimizations.
* Expand and refine pipelines for defining, enumerating, and screening virtual libraries based on optimized reactions and available building blocks.
* Design approaches for rapid inclusion of new reaction classes into predictive models and automation protocols.
Requirements
* PhD in chemistry, data science, or a related field.
* Extensive experience with cheminformatics and software development.
* Solid understanding of organic chemistry and chemical processes.
* Experience with modern AI/ML approaches and basic automation techniques.
* Excellent written and verbal communication skills (English).
About Us
* Opportunity to conduct cutting-edge research at the intersection of AI-assisted drug discovery, virtual screening, and automated synthesis.
* Collaborative work environment with both synthetic and computational chemists from academia and industry.
* Applied research project with high-impact scientific and commercial goals.
What We Offer
* A highly supportive and multidisciplinary team environment.
* An inclusive culture that promotes equality of opportunity and values diversity.