**Job Title:** Director Non-Clinical PK/PD
Location: Basel, Switzerland
Salary Range: CHF160,000 to CHF180,000 per year, with company bonus
Main Responsibilities:
1. Lead PK/PD activities in non-communicable diseases team, including complex multi-specific formats.
2. Contribute expertise and scientific skills to project teams and strategic discussions.
3. Collaborate as a leader and hands-on experimental designer/executor with consultants and CRO partners.
Additional Responsibilities:
1. Design and implement integrated non-clinical PK/PD strategies from research through early clinical development.
2. Manage, analyze, review, summarize, interpret, report, and communicate PK/PD study results, including optimization strategies.
3. Oversee, author, and review non-clinical regulatory documents and reports for compliance.
Requirements:
1. PhD in Pharmaceutical or Life Sciences with 8–10 years of experience in non-clinical development in biotechnology/pharmaceutical industry with large molecule expertise.
2. Proven track record advancing biotherapeutic candidates through non-clinical development, IND submission, and beyond.
3. Strong experience in non-clinical development of therapeutic proteins, with broad expertise in PK/PD, pharmacology, and safety principles.
4. Familiarity with GLP regulations, guidelines, and regulatory requirements for non-clinical development, along with experience in regulatory submissions and interactions.
5. Relevant expertise in immuno-oncology; additional experience in cardiometabolic diseases is a plus.
Language Skills:
Fluent English ability – C1 written and verbal required.