Bioinformatics Engineer (Proteomics and Functional Genomics)
Bioinformatics Engineer (Proteomics and Functional Genomics), London or Lausanne
We are looking for bioinformatics engineers with various levels of experience - Mid through to Senior, Principal, Staff or equivalent levels.
We are here to advance human health, by reimagining drug discovery with the power and pace of artificial intelligence.
This is an exciting opportunity for you to work on a greenfield ML-based software platform and ambitious Computational Biology research programme that will transform the biopharmaceutical world as we know it.
Your impact
Working in a highly creative, iterative environment, you will be partnering with leading engineers, scientists and ML researchers to build the critical platform driving this transformation. This is a newly created role and you will need to use your previous experience and show initiative in order to fully carve out your contribution.
What you will do
* Large-scale biostatistical analysis and harmonisation of proteomics datasets.
* Implement and apply tools and methodologies for mass spectrometry proteomics.
* Implement and apply tools and methodologies for functional analysis (e.g., pathway analysis, gene set enrichment analysis, protein domain analysis, protein-protein interaction networks).
* Develop and operate bioinformatics pipelines for functional genomics and proteomics.
* Develop and curate robust data models and integration strategies to ensure data consistency, quality, and interoperability.
* Collaborate with computational biology and chemistry groups, providing guidance and support for their initiatives.
* Provide training and guidance on proteomics, functional genomics, data resources, and analysis tools to the organization.
Skills and qualifications
* Experience with large scale data harmonisation and normalisation.
* Experience working with proteomics data (e.g., mass spectrometry data analysis pipelines).
* Experience working with genomics data (e.g. variant calling, RNAseq analysis).
* Knowledge of functional analysis tools and methodologies.
* Proficiency in programming languages like Python or R, with experience developing bioinformatics pipelines.
* Knowledge of network analysis methodologies.
* PhD degree in Bioinformatics, Computational Biology, or a related field, or equivalent practical experience.
Nice to have
* Knowledge of the pharmaceutical industry, ideally with a focus on drug discovery
* Experience working with cloud computing environments.
* Experience with workflow management systems (e.g. nextflow, snakemake).
* Exposure to machine learning concepts and their application in functional genomics and proteomics.
Culture and values
We are guided by our shared values. It's not about finding people who think and act in the same way. These values help to guide our work and will continue to strengthen it.
Thoughtful: Thoughtful at Iso is about curiosity, creativity and care. It is about good people doing good, rigorous and future-making science every single day.
Brave: Brave at Iso is about fearlessness, but it’s also about initiative and integrity. The scale of the challenge demands nothing less.
Determined: Determined at Iso is the way we pursue our goal. It’s a confidence in our hypothesis, as well as the urgency and agility needed to deliver on it. Because disease won’t wait, so neither should we.
Together: Together at Iso is about connection, collaboration across fields and catalytic relationships. It’s knowing that transformation is a group project, and remembering that what we’re doing will have a real impact on real people everywhere.
Creating an inclusive company
We believe that to be successful we need our teams to reflect and represent the populations we are striving to serve. We’re working to build a supportive and inclusive environment where collaboration is encouraged, learning is shared and every employee feels like they truly belong. We value diversity of experience, knowledge, backgrounds and perspectives, and harness these qualities to create extraordinary impact.
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