Postdoc Position in the Development of In Vitro Models of the BBB
Client:
Bio Engineering Laboratory & Novartis
Location:
Basel
Job Category:
Other
Job Reference:
8cd109bf96c0
Job Views:
9
Posted:
21.01.2025
Expiry Date:
07.03.2025
Job Description:
In this project, we aim at exploring how in vitro models can be leveraged to improve preclinical drug selection, particularly for gene therapy development. Building on the group expertise in blood-brain-barrier platforms, the postdoc will develop new in vitro models of the human and mouse blood-brain-barrier and benchmark these models for preclinical and clinical investigations. After validation, the postdoc will collaborate with researchers at Novartis AG to test whether the developed models can expedite the selection of candidate therapeutics, especially for gene therapy.
Your Profile:
The successful candidate should have a background in bioengineering, biotechnology, or related fields, with a preference for experience in microfluidics, advanced in vitro models, transport across endothelial barriers, and viral vectors. Experience in optical microscopy is highly beneficial. Knowledge of standard molecular biology techniques and NGS technologies will be advantageous. Good communication skills and a proactive work attitude are required for working in the interdisciplinary field of preclinical testing and drug development. The postdoc must be able to fluently communicate in English (oral and written) and be willing to work in a highly interactive and collaborative international environment. The researcher will work at the intersection of academic and industrial research with access to resources and expertise from both institutions.
Job Training Programs:
Academic excellence, a professional work attitude, and a self-driven nature are expected. The position is fully funded for an initial 2 years, with a possible extension to up to 4 years. The starting date is flexible but must be before 10-.
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