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A healthier future drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love.
The Opportunity
We invite you to join our Postdoctoral Fellow in the Roche Pharma Research and Early Development Data and Analytics Department, focusing on generative AI and pharmacodynamics modeling with the Ophthalmology Precision Medicine (OPM) project, a cornerstone of pRED's ophthalmology strategy.
You will collaborate with a dedicated team of experienced scientists and clinicians to develop computer vision models capable of analyzing and predicting the timecourse of an individual patient's imaging biomarker signature, in order to predict disease progression, response to treatment, and to enable detailed insights into pharmacodynamics at the individual eye level.
The role focuses on analyzing Optical Coherence Tomography (OCT) retinal images sourced from both a home monitoring device and clinical instruments. This initiative is critical to differentiate products, enhance market placement, and demonstrate predicted treatment outcomes to physicians and patients under various scenarios, ultimately improving overall clinical trial efficiency and patient outcomes.
You will be supervised by scientists at Roche, as well as an independent academic expert as partner. The duration of the RPF project is initially set for two years, with the possibility of extension for a third year.
You are a PhD degree graduate in a Data Science related field, such as Statistics, Computer Science, Biomechanics, or Biomedical engineering. To be eligible for a Roche Postdoctoral Fellowship, you must be within the first four years of completing your PhD in a relevant field at the start of the project.
Your Expertise:
* A PhD in a relevant field such as artificial intelligence, imaging, sensors, biology, pharmacology, biomedical engineering, or a related discipline
* Excellent understanding of quantitative data analysis
* Prior experience with applying relevant software for imaging data analysis
* Prior experience with generative AI in imaging, such as GANs or diffusion models
* Excellent communication skills, with the ability to present complex information clearly
* Fluency in English
* Publication record demonstrating independent and creative research
Additional Experience Preferred:
* Prior experience or a good understanding of retinal biology
* Prior experience with in-silico modeling, or a motivation to learn the basics for this project
* A basic understanding of pharmacokinetic and pharmacodynamics in drug development
Your Responsibilities:
* Collaborate with host teams and other stakeholders to develop and evaluate potential analysis techniques and applications
* Design, build and interpret data analysis algorithms to address selected research questions, including data pre-processing
* Prepare scientific communication content to share the results of the project with a wider community
You have very good interpersonal skills, are able to build good working relationships, and are an outstanding teammate. Your experience and investigative attitude allow you to work independently and design new scientific methodologies.
You have been actively engaged in scientific research since your PhD and are ready to start an RPF postdoctoral activity no later than 4 years after completing your PhD.
Start Date:
The start date of this fellowship is in May 2024, or on availability. Please indicate your preferred starting date on your motivation letter.
Please submit your application including a CV, motivation letter, publication list, and if available, a copy of your PhD certificate.
This position is sponsored by the Roche Postdoctoral Fellowship Programme, aiming to build and maintain Scientific Leadership of the future and provide leading Roche scientists with the opportunity to collaborate with talented postdoctoral researchers and leading academic research groups worldwide.
More information about the RPF Programme: https://careers.roche.com/global/en/the-roche-postdoctoral-fellowship-programme
About Us:
A healthier future drives us to innovate. Together, over 100'000 employees across the globe are dedicated to advance science and ensure everyone has access to healthcare today and for generations to come. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact.
Besides extensive development and training opportunities, we offer flexible working options, 18 weeks of maternity leave and 10 weeks of gender-independent partnership leave. Our employees also benefit from multiple services on site, such as child-care facilities, medical services, restaurants, and cafeterias, as well as various employee events.
We believe in the power of diversity and inclusion, and strive to identify and create opportunities that enable all people to bring their unique selves to Roche.