Job Description Summary
Location: Basel, Switzerland
Role Purpose:
We are seeking a highly motivated and skilled Lab Technician to join our Chemical Structure Investigation (CSI) lab. The ideal candidate will possess a strong scientific mindset and curiosity, along with a broad skill-set in high-end analytical instrumentation. This role offers an exciting opportunity to work on a variety of projects, from early-phase development to marketed products, and to gain a broad set of skills and experiences.
Key Responsibilities:
1. Planning and execution of the full impurity elucidation workflow, including isolation and characterization.
2. Develop and conduct HPLC-HRMS measurements and HRMS data analysis.
3. Develop Prep-HPLC methods for the isolation of small molecules, synthetic oligonucleotides and RLTs (including DP formulations) at milligram-scale.
4. Measure and interpret 1D and 2D-NMR spectra, including quantitative NMR (qNMR).
5. Perform and develop HPLC-UV analysis.
6. Use specific software like Chromeleon, OpenLab, XCalibur, or UNIFI/Waters Connect for data analysis and processing.
7. Communicate results effectively with internal customers and collaborate with team members.
8. Clean and traceable documentation of the results.
Qualifications:
1. Strong scientific mindset and curiosity.
2. Broad skill-set in high-end analytical instrumentation.
3. Experience in HPLC-HRMS measurement and HRMS data analysis.
4. Experience in developing Prep-HPLC methods and analyzing DS and DP.
5. Experience in measuring and interpreting 1D and 2D-NMR spectra, including qNMR.
6. Experience in HPLC-UV analysis.
7. Experience with GC-FID and GC-MS.
8. Familiarity with other qualitative analysis tools (IR, RAMAN, XRF, XRPD, SEM, etc.) is a plus.
9. Experience with specific software like Chromeleon, OpenLab, XCalibur, or UNIFI/Waters Connect.
10. Excellent communication skills to interact with internal customers and communicate results.
11. Ability to work independently and organize one's own work.
12. Strong team player with the ability to collaborate effectively.
13. We are looking for candidates with completed apprenticeship as laboratory technician (Laborant/-in Chemie EFZ). The position is also open to applicants with BSc in the field of analytical chemistry or equivalent, with laboratory experience.
Commitment to Diversity and Inclusion: Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.
Accessibility and Accommodation: Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to inclusion.switzerland@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message.
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