Job Description
We are part of Roche's Pharmaceutical Research and Early Development organisation (pRED), where we create transformative medicines for patients tackling the world's toughest unmet healthcare needs.
In pRED, our mission is to transform science into medicines, fostering a culture defined by curiosity, responsibility, and humility. Our talented people are empowered to bring forward life-changing innovation at speed.
About Our Team
You will join the Institute of Human Biology (IHB), which harnesses human model systems in drug discovery and development, as well as personalized medicine. We bridge academic and pharmaceutical research, connecting biologists, engineers, and data scientists worldwide.
Key Responsibilities
1. Develop a 3D co-culture model of the brain incorporating neurons and glia.
2. Establish imaging-based assays measuring glial function in 3D co-culture models.
3. Characterize cell lines with disease-relevant mutations thoroughly.
4. Design, execute, analyze, interpret, and communicate experiments independently.
5. Publish scientific findings and present at conferences.
Your Profile
* Hold a PhD in Bioengineering, Neuroscience, or relevant areas.
* Have hands-on expertise on stem-cell derived models of human brain cell types.
* Experience working with hydrogel-based 3D culture models.
* Experience developing imaging-based functional assays including image quantification workflows.
* Knowledge of cellular mechanisms driving Alzheimer's disease pathology.
* Strong critical thinking, communication, organization, and presentation skills.
* Ability to navigate matrix environments influencing experts to move projects forward.
* Driven by scientific curiosity and commitment to patients.
Our Commitment
Roche prioritizes employee growth, encouraging talent recognition and aptitude. We support employees in their personal journeys, providing a safe space for reflection and decision-making. Roche values diversity and equal opportunity, embracing different perspectives and challenging the status quo.