About Us
Roche fosters diversity, equity and inclusion, representing the communities we serve. When dealing with healthcare on a global scale, diversity is an essential ingredient to success. We believe that inclusion is key to understanding people's varied healthcare needs.
We are united by our mission to transform science into medicine. Together, we create a culture defined by curiosity, responsibility, and humility, where our talented people are empowered and inspired to bring forward extraordinary life-changing innovation at speed.
At Roche, more than 100,000 people across 100 countries are pushing back the frontiers of healthcare. Working together, we've become one of the world's leading research-focused healthcare groups.
The Position
In Roche's Pharmaceutical Research and Early Development Organisation (pRED), we make transformative medicines for patients in order to tackle some of the world's toughest unmet healthcare needs.
You will join Roche's Institute of Human Biology (IHB), an organization within pRED whose goal is to harness and advance the use of human model systems in drug discovery and development, and personalized medicine.
We partner and collaborate with leading scientific institutions worldwide to tackle grand challenges by assembling, funding, and leading interdisciplinary teams of experts to work on highly ambitious and complex scientific questions.
The Opportunity
We are offering an outstanding opportunity for an experienced associate to contribute to our mission of disrupting the traditional drug discovery process by advancing more predictive human model systems.
You will be responsible for all aspects of our cell line and organoid biorepository and will contribute to further improving our capabilities for biobanking.
You will work in close collaboration with multidisciplinary experts to establish workflows for organoid generation, expansion, banking, molecular profiling, and documentation.
* Establish and Maintain Cell Banks and complex in vitro models (cIVMs): Develop and sustain master and working cell banks, as well as complex cIVMs, ensuring comprehensive documentation and tracking of model usage and storage conditions.
* Quality Control (QC) and Testing: Implement routine quality control measures, including contamination testing and cell line authentication, to maintain specimen integrity and advance QC processes to state-of-the-art levels for both cell lines and cIVMs.
* Regulatory and Compliance: Ensure adherence to standard operating procedures (SOPs), regulatory guidelines, and quality standards, while supporting ethical compliance in the use of embryonic stem cells (ESCs), induced pluripotent stem cells (iPSCs), and cIVMs.
* Specimen Lifecycle Management: Oversee the entire lifecycle of specimens, including cIVMs, from acquisition to distribution, ensuring efficient biosample fulfillment, customer communication, and inventory management.
* Tissue Processing and Protocol Development: Conduct quality checks and handle tissue distribution, while developing standardized protocols for the isolation and culture of various cell types, such as endothelial cells and astrocytes, to support downstream applications and enhance cIVM capabilities.
Your Qualifications
You hold a university degree, preferably a BSc or MSc, in biology, life sciences, or a related field, or possess equivalent professional experience in stem cell biology, or complex in vitro model development.
You have extensive experience and deep knowledge of cell culture, organoid techniques, and complex in vitro models. You are proficient in organoid differentiation protocols, including quality control, documentation, and regulatory compliance.
You have demonstrated the ability to navigate a matrix environment effectively, influencing, leading, advising, or consulting with experts to advance projects and lead the lifecycle of specimens, including acquisition, processing, and distribution.
What We Offer
Besides extensive development and training opportunities, we offer flexible working options, 18 weeks of maternity leave and 10 weeks of gender independent partnership leave.
Our employees also benefit from multiple services on site such as child-care facilities, medical services, restaurants and cafeterias, as well as various employee events.
We believe in the power of diversity and inclusion, and strive to identify and create opportunities that enable all people to bring their unique selves to Roche.
Roche is an Equal Opportunity Employer.